American Board of Psychiatry and Neurology (ABPN) Practice Exam

The correct answer is the specifier indicating "with onset during withdrawal." This specifier is significant because substance-induced anxiety disorder can arise as a direct result of withdrawal from certain substances. Symptoms can develop shortly after the reduction or cessation of substance use, which highlights the connection between the withdrawal process and the emergence of anxiety symptoms.

This is particularly relevant in cases where individuals might experience heightened anxiety as their bodies adjust to the absence of the substance, capturing the nature and timing of anxiety symptoms relative to substance use and withdrawal. As a result, using this specifier helps clinicians understand the context in which the anxiety symptoms occur, allowing for appropriate diagnosis and treatment strategies that address both the anxiety and the underlying substance use issues.

Other specifiers might relate to general anxiety patterns or panic attacks, but they do not specifically capture the critical relationship between withdrawal and the onset of anxiety symptoms.